TP53 and plasmacytoma: The following clinical data were recorded as previously described: routine blood tests, creatinine, lactate dehydrogenase, serum protein electrophoresis (SPE), (serum and urine) immunofixation electrophoresis (IFE), extramedullary plasmacytoma (EMP), bone marrow plasma cell (BMPC) percentage, immunophenotype of plasma cell, bone marrow chromosome karyotyping by G-banding and FISH examination for RB1 deletion, 1q21 amplification, IgH rearrangement, P53 deletion, and D13S319 deletion [13].