It also effectively inhibited Glutamic-Oxaloacetic Transaminase-1 (GOT1) in a non-competitive mode and can induce glutamine metabolism disorder and redox state imbalance of PDAC cells by specifically targeting GOT1, thereby it inhibits the cell growth, invasion, prevents the migration, and induces apoptosis35.It helps the patients afflicted with lifelong disease36. This evidence concerns the gene GOT1 and Other metabolic disease.