ADGRL3 and attention deficit-hyperactivity disorder: For example, Adgrl3−/− rats and mice, and both adgrl3.1 antisense morpholino oligonucleotide (MO) knock-down and adgrl3.1−/− knock-out zebrafish larvae, display persistent hyperactivity [24, 27], which is rescued by both stimulant and non-stimulant ADHD treatments (e.g., the dopamine (DAT) reuptake inhibitor methylphenidate [28] and the noradrenaline (NET) reuptake inhibitor atomoxetine [24, 28, 29]).