Erythema was characterized by a bolstered signature of immediate early genes (NR4A1, FOSL1, FOSB, ATF3, NR4A2) and immune system (CD163, C1QB, C1QC, THY1, MS4A7) that are inferentially expressed mainly in keratinocytes and myeloid cells, respectively, in skin tissue, along with Treg specific genes (CCR4, CNTNAP1, DUSP4, LMNA, PI16) in PBMC. The gene discussed is C1QC; the disease is Erythema.