HSP90 hasbeen shown to play a role in the regulation of motility and capacitationof spermatozoa.58,59 Pharmacological inhibition ofHSP90 reduces porcine sperm motility,60 and its loss during the freezing correlates with a diminution inmotility of sperm in bovine.61 Kasimanickamet al. found that HSP90 was overexpressed in HF bull sperm,24 whereas our results showed a negative associationbetween the overexpression of HSP90 isoforms and motility in the LFgroup. This evidence concerns the gene HSP90AB1 and hydrops fetalis.