Plasmacytoma variant 1 (Pvt1) represents a lncRNA transcribed approximately 50 kb downstream of the myeolocytomatosis (Myc) oncogene that has been initially identified as a hotspot for chromosomal translocations in murine and later also in human lymphomas (Cory et al. 1985; Graham and Adams 1986; Graham et al. 1985). The gene discussed is MYC; the disease is lymphoma.