Interestingly, later studies (Marney et al. 2021, 2022) revealed that the Dino/Cdkn1a locus represents a tumor suppressor locus as loss of Dino can promote lymphoma in an Eμ-Myc mouse model as well as induce the formation of a subset of spontaneous tumors, including sarcomas and lymphomas. This evidence concerns the gene DINOL and lymphoma.