PVT1 and breast carcinoma: Since the human genomic locus on chromosome 8 (8q24), including the PVT1 gene, has been shown to be amplified in human breast cancer (Curtis et al. 2012) and PVT1 itself has been reported to stabilize the MYC protein (Tseng et al. 2014), PVT1 has been described as a potential oncogene.