The significant differences between the two groups were shown before PSM analysis, including age, gender, BMI, admission type, AKI stage, WBC, hemoglobin, albumin, bicarbonate, hypertension, diabetes, CKD, CHF, myocardial infarction, ventilation, hemodialysis, SOFA, SAPS-II, CCI, heart rate, MAP, respiratory rate, temperature and SpO2 (Table 1). The gene discussed is ALB; the disease is chronic kidney disease.