AKT1 and pulmonary fibrosis: These fatty acids play a role in inhibiting the epithelial-mesenchymal transition (EMT) process by suppressing the PI3K/Akt/mTOR signaling cascade (B. Chen et al., 2021; D; Chen et al., 2020).Therefore, Tan may directly or indirectly act on PI3K, inhibiting the activation of the PI3K/Akt signaling pathway, and subsequently inhibiting the epithelial-mesenchymal transition (EMT) process in pulmonary fibrosis.