Despite atopy, patients with asthma and CRSwNP showed higher blood eosinophilia (P = .024), Feno levels (P < .001), and total serum levels IgE (P < .001) than those with other sinonasal phenotypes (see Table E1 in this article’s Online Repository at www.jaci-global.org). The gene discussed is IGHE; the disease is asthma.