MYCN and neuroblastoma: Further cell proliferation assays showed that the treatment of NB cells with increased dosages of either OICR-9429 or UNC0642 alone reduced the number of viable NB cells (Fig. 7G), while the combination of OICR-9429 and UNC0642 synergistically reduced NB cell proliferation with an average bliss synergy score greater than 10 in all tested MYCN-amplified NB cell lines (Fig. 7G,H).