In addition to Snx9, various proteins of the Snx family were detected to be upregulated in ZIKV-infected sEVs, and further analysis of Snx6 and 9 showed that disruption of MDV biogenesis affects ZIKV replication and infectivity, in addition to increasing the amount of cytosolic mtDNA following infection (Figure 7). This evidence concerns the gene ANXA7 and infection.