CXCL8 and infection: Based on the RNASeq results, sixteen cytokines were selected for the analysis and included cytokines induced in the presence of either stimulus (TNF-α, CCL5, CXCL8, CCL4, IL-15, IL-1β, IL-6, CCL3, CSF3), induced exclusively by hSAA-1 (CCL3, IL-12β, CCL2), induced exclusively by infection with M. tuberculosis (CSF2, IL-27, CXCL10), and induced only in the presence of both stimuli (CCL7), (Table S3).