Since the IL-23/T17 axis cytokine sources (T-cells, DCs, and KCs) were decreased in the predetermined volume of skin biopsy tissue (6 mm punch), total skin transcriptome of IL-23/T17 axis cytokines (IL17A and IL26 from T-cells, IL23A, IL12B, and IL20 from DCs, and S100A8 and IL36 from KCs) was decreased in posttreatment psoriasis lesional skin compared to pretreatment psoriasis lesional skin (Figure 2B). This evidence concerns the gene IL26 and psoriasis.