2) The expression of CD1C and CD14, which are genes of a CD1c+ CD14+ DC subset that suppresses antigen-specific T-cell responses (53, 54), was increased in posttreatment psoriasis lesional skin semimature DCs compared to pretreatment psoriasis lesional skin semimature DCs (Figure 5B, p < 0.05). This evidence concerns the gene CD1C and psoriasis.