KC hyperproliferation [KRT16 staining (27)], T-cell numbers (CD3 staining), and DC numbers (ITGAX (CD11c) staining) were decreased in psoriasis lesional skin after 12 weeks of anti-IL-17A monoclonal antibody injections (posttreatment) compared to pretreatment psoriasis lesional skin of the same patients (Figure 2A, p < 0.05). This evidence concerns the gene ITGAX and psoriasis.