Inhibition was not observed when iDCs with captured HIV-1 were co-cultured with a R5-tropic HIV-1-resistant cell line, CEMss-CCR5-CR2N cells (Figure 5), indicating that the trans-infection neutralization of R5-tropic HIV-1 replication in iDCs is not due to the infection resistant phenotype of GPI-scFv X5-transduced CEMss-CCR5 cells. The gene discussed is CCR5; the disease is infection.