CD8A and angioimmunoblastic T-cell lymphoma: Therefore, in this study, we analyzed the correlations among CD8+TILs and expression of IC, exhaustion-related biological changes, and prognosis of patients with AITL, to elucidate the exhaustion status of CD8+TILs in AITL and to further explore its influence on AITL occurrence and development as well as to determine possible therapeutic targets.