NK cells were identified by cytolysis-related enzymes (e.g., Gzma, Gzmb, Prf1) and receptors (e.g., Klre1, Klrb1c), and BC was marked with early B-associated genes (e.g., Cd79a, Igkc, and Ebf1) (Figure 5B). The gene discussed is PRF1; the disease is breast cancer.