Despite the lack of differences in the parameters of left ventricular function, significantly higher levels of myocardial necrosis [hs-cTnT H1 7.83 (3.96–15.22) ng/ml vs. 4.97 (2.88–9.37) ng/ml, p = 0.01] and markers of heart failure [NT-proBNP 198.0 H1 (93.0–475.0) pg/ml vs. 131.5 (46.3–293.0) pg/ml, p = 0.004] were observed in the group of severely ill patients. Here, NPPB is linked to Myocardial necrosis.