Recently, we investigated the phenotypic heterogeneity of four GBM cell lines (U87MG, T98G, U251MG, and DBTRG-05MG) and revealed some discrepancies in the results from in vitro assays following the ectopic overexpression of WW domain-containing oxidoreductase (WWOX) (Kaluzinska-Kolat et al., 2023; Varricchio et al., 2023). Here, WWOX is linked to glioblastoma.