The latest research reported that the main protease of COVID-19 could target several selenoproteins, including TR1, γ-glutamate cysteine ligase (GCLC) and SELENOP, promote proteolytic degradation and eventually disrupt the Thioredoxin and Glutaredoxin Redox Cycles, the necessary process of DNA production (151). This evidence concerns the gene GLRX and COVID-19.