NEFH and in situ carcinoma: A cross-sectional biomarker study found plasmatic phosphorylated (p)NfH level to be positively correlated with 8-hydroxy-2′-deoxyguanosine (8-OHdG), gadolinium (Gd)-enhancing lesion, EDSS score, BBB permeability, and disease progression in CIS and RRMS patients (Ljubisavljevic et al., 2016).