Notably, CYP3A4, CYP1A1, CYP2E1, CYP1A2, NR1I2, CYP2C9, CYP2A6, and UGT2B15 were identified to be primarily associated with the modulation and function of IAPs in HCC. The gene discussed is NR1I2; the disease is hepatocellular carcinoma.