S100A10 and neoplasm: Consistently, in vivo xenograft experiments revealed that on day 27, the tumor weights in the sh-NC and sh-S100A10 groups were 302.07 ± 36.91 mg and 120.93 ± 25.00 mg (P < 0.01) (Fig. 5a-b), respectively, whereas the respective tumor volumes were 435.55 ± 76.63 mm3 and 167.81 ± 37.28 mm3 (P < 0.01) (Fig. 5c).