Initially, the expression of S100A10 was assessed across all cancers in the TIMER 2.0 database, revealing it to be overexpressed in CESC, CHOL, ESCA, GBM, HNSC, KIRC, KIRP, LIHC, PAAD, STAD, THCA, and UCEC, whereas S100A10 downregulation was detected in BRCA, COAD, KICH, LUAD, LUSC, PCPG, and READ (Fig. 1a). The gene discussed is S100A10; the disease is cancer.