Kang et al. 64 discovered that an extract of Auricularia auricula, by inhibiting PRDX1, diminished the levels of total glutathione (GSSG/GSH) and superoxide dismutase (SOD), thereby inactivating antioxidant enzymes, impeding cells from processing reactive oxygen species, and promoting apoptosis of liver cancer cells. Here, SOD1 is linked to liver cancer.