PRF1 and gastric cancer: Co-cultured with CD36 overexpressed gastric cancer cells, Jurkat T cells down-regulated the expression of BATF2, MYB, and T cell effector molecules (PRF1, GZMB, TNF, and IFNG) (Fig. 9A, B) and enhanced the proliferation of gastric cancer cells (Fig. 9C-E), indicating the indirect impact of malignant CD36 on gastric cancer development was caused by the down-regulation of T cell function.