WWP2 and endometrial cancer: We explored how macrophages shield lesions from immune surveillance while promoting pathological cell growth, invasion, and metastasis (32), and identified 9 key macrophage genes, including GINS3, PRMT2, MERTK, WWP2, NEK6, NACC1, NR1H3, ATP2A2, and TM4SF19, some of which have not been previously reported in the context of endometrial cancer.