In the low-risk group, we observed significantly higher infiltration levels of various immune cell types, including activated dendritic cells (aDCs), CD8+ T cells, dendritic cells (DCs), macrophages, neutrophils, plasmacytoid dendritic cells (pDCs), T helper cells, T follicular helper cells (Tfh), T helper 1 cells (Th1), tumor-infiltrating lymphocytes (TILs), and regulatory T cells (Treg) (Figure 10A). This evidence concerns the gene CD8A and neoplasm.