Increased values of CRP (OR: all = 1.276, SIC-negative = 1.616), blood glucose (OR: all = 1.370, SIC-negative = 1.315) and Hb (OR: all = 1.316, SIC-negative = 1.425) are positively associated with the development of AF in the overall sepsis and the SIC-negative cohorts. This evidence concerns the gene CRP and atrial fibrillation.