KRAS and Zika virus infectious disease: Together, the NS2B/NS3 protease complex cleaves theviral polyprotein into individual proteins that are necessary forviral replication, including the viral capsid protein and the RNA-dependentRNA polymerase.21,22 The NS2B/NS3 protease also playsa critical role in viral maturation and assembly,23,24 making it an attractive target for the development of antiviraltherapies against Zika virus infection.