LncRNA SNHG1 (small nucleolar RNA host gene 1) has been reported to repress miR-16-5p-mediated p38 MAPK and NF-κB pathways, such as p-p65, ERK1/2 and p-p38, leading to attenuation of IL-1β-mediated osteoarthritis (Lei et al., 2019). The gene discussed is IL1B; the disease is osteoarthritis.