Research revealed that ROR1 is significantly upregulated at the transcriptional and translational levels, and this upregulation correlates with larger tumor size, lymphatic metastasis, and advanced TNM (Tumor (T), Nodes (N), and Metastases (M)) stages (II and IV) (Zhang et al., 2012; Balakrishnan et al., 2017). Here, ROR1 is linked to neoplasm.