Cancer progression is influenced by the EGFR-mediated and Wnt signaling pathways, which are interconnected through the PI3K/AKT/mTOR pathway ROR1 is associated with advancing aggressive phenotypes in breast cancer, including triple-negative breast cancer (TNBC) (Bemani et al., 2022; Nadanaka et al., 2022). This evidence concerns the gene ROR1 and breast cancer.