Histopathologically, LAMA3 alterations were associated with patients with later stages of PAAD (p = 4.6 × 10−10, q = 1.7 × 10−8), whereas associations between LAMB3 and LAMC2 and the disease stage were less robust but suggest a slight association with early disease (p = 2.8 × 10−4, q = 4.4 × 10−3; p = 0.02, q = 0.27) (Figure 6C). This evidence concerns the gene LAMA3 and pancreatic adenocarcinoma.