Bollinger et al. validated a clinical prediction rule to aid in the diagnosis, which includes dry cough, fever >39.4°C, C-reactive protein ≥187 mg/L, lactate dehydrogenase ≥225 mmol/L, hyponatremia (<133 mmol/L), and platelet counts <171 G/L. The gene discussed is CRP; the disease is Hyponatremia.