Systemic hyperglycemia induced increased glucose uptake via glucose transporter, GLUT1, in neutrophils to promote the production of neutrophil‐derived alarmins, S100A8/S100A9, which drive myelopoiesis via interaction with the glucose‐inducible receptor for advanced glycation end products (RAGE) on common myeloid progenitor cells.56 This evidence concerns the gene S100A9 and Hyperglycemia.