The relevance of histone lactylation to cardiovascular disease is confirmed by its ability to regulate early homeostatic gene expression (including leucine‐rich alpha‐2‐glycoprotein 1 (Lrg1), vascular endothelial growth factor A (Vegf‐a), and interleukin‐10 (Il‐10)) in the bone marrow and peripheral monocytes promoting cardiac repair post‐myocardial infarction.35 The gene discussed is VEGFA; the disease is myocardial infarction.