Depletion of HULC decreased angiogenesis, proliferation, and invasion by inhibiting the phosphorylation of ERK/AKT/mTOR and downstream target eIF4E.125 The UCA1 lncRNA was found to support the increased glycolysis due to the activation of hexokinase 2 via the mTOR-STAT3/miRNA143 axis in bladder cancers.126 ZNNT1 lncRNA is localized on chromosome-8 and has only a single exon. The gene discussed is MTOR; the disease is urinary bladder cancer.