Mechanistically, H19 interacts with 4E-BP1 which hampered the 4E-BP1 interaction with Raptor.117 This study displayed the potential role of the H19-mTOR-4E-BP1 axis in pituitary tumors.117,118 LINC00963 overexpression was associated with poor prognosis, cell proliferation, invasion, and metastasis in non-small cell lung carcinoma (NSCLC). This evidence concerns the gene RPTOR and non-small cell lung carcinoma.