Similarly, further investigation of IDI2 gene and protein expressions in skeletal muscle tissue along with breath isoprene expressions under various exercise trainings and in individuals with muscle dystrophy and risk of rhabdomyolysis, e.g., under statin interventions or injury may reveal unexplored frontiers in sports/fitness and musculoskeletal medicine and inter-organ metabolic cross-talk. Here, IDI2 is linked to rhabdomyolysis.