CASP3 and Familial prostate cancer: Finally, 24 of the 26 articles relating to UA and PCa reported data outcomes on the mechanistic pathways (Supplemental Table 5), which we used to perform descriptive and qualitative analysis.7,185, , , , , , , , , , , , , , , , , , , , , –207 The word cloud of the most common pathways affected in prostate cancer is displayed Figure 5(b) and Supplemental Table 6, with the pathway involving caspase 3/caspase 9 as the most common (n = 10/24, 41.7%).