YAP1 and anemia (phenotype): In the mammalian system, YAP plays a role during mouse erythropoiesis as the conditional knockout of both YAP and TAZ, a YAP homolog, leads to the development of anemia in those mice [16, 17], while the overexpression of YAP causes the rapid expansion of mouse erythroid progenitors both in vivo and in vitro [18].