To summarize, our analysis identified six risk proteins (NAMPT, TIE1, CBR1, PDE4D, PAFAH1B2, NCF2) and seven protective proteins (FSTL1, PTPN4, SOCS3, GZMB, GPC1, C1QC, FCGR3B) that are causally associated with MM risk. This evidence concerns the gene SOCS3 and Miyoshi myopathy.