This individual was under treatment of several comorbidities, including hypertension (treated with angiotensin-converting enzyme inhibitor), cardiomyopathy (using diuretics and statins), type 2 diabetes mellitus (using three different anti-diabetic drugs), and alcohol abuse, and thus, the underlying cause of renal failure was probably multifactorial. The gene discussed is ACE; the disease is cardiomyopathy.