These findings are consistent with previous reports that CD8 T cells are elevated in diagnosed PD cases and that density is positively correlated with neuronal death.[53] In addition, it was reported that “naïve” T cells, CD4 + T cells, and CD19 + B cells were reduced while cytotoxic CD8 + T cells were elevated in PD brain. The gene discussed is CD4; the disease is Parkinson disease.