In addition, combined with the difference analysis results of immune infiltration and the correlation results of copper death immune infiltration, it is not difficult to find that CD4 + T cells, dendritic cells, myeloid suppressor cells, monocytes, CD8 + T cells, B cells, macrophages and eosinophilic cells may play an important role in the regulation of diabetes mellitus by copper death gene. This evidence concerns the gene CD4 and diabetes mellitus.