Along this line, several natural compounds, such as curcumin, isoliquiritigenin, and anthocyanins, have been reported to activate Nrf2/HO‐1 pathway to mitigate the inflammatory and oxidative damages in the animal models of SCI, pancreatitis, and Alzheimer's disease.29, 42, 43. The gene discussed is HMOX1; the disease is Alzheimer disease.