NLRP3 and atrial fibrillation: Then, the immunohistochemical staining of inflammasome‐related protein (for instance, NACHT, LRR, and PYD domains‐containing protein 3, NLRP3) is performed in combination with enzyme‐linked immunosorbent assay (ELISA) of corresponding proinflammatory factors to assess the immunomodulatory effects of AF.