SOD2 and colitis: In this aspect, Lactobacillus plantarum ZS62, the oral administration of which alleviated the severity of DSS-induced colitis in mice, was proved to upregulate the levels of CAT and T-SOD in the serum, and the expression of Cu/Zn SOD, Mn SOD, GSH-Px, CAT in inflamed colon tissues [26].