NF1 and digestive system neoplasm: The present patient carried a termination mutation in exon 23 of the NF1 gene c.3052delT as well as a frameshift mutation in exon 10, c.1131del1134del.pI377fs, which predicts the occurrence of a premature stop codon and abnormal gene arrangement, resulting in the loss of all functional domains of the neurofibromin protein, which may be the cause of gastrointestinal tumors.