The mutant protein levels were comparable to those of breast cancer cell lines harboring missense TP53 mutations such as HCC70 (TP53R248Q), MDA-MB-468 (TP53R273H), MDA-MB-231(TP53R280K), AU565 (TP53R175H), and SK-BR-3 (TP53R175H). The gene discussed is TP53; the disease is breast cancer.