The possible explanations are as follows: (1) PLC was a predictor of poor prognosis in the univariate analysis, but not in the multivariate analysis, indicating a potential indirect association between PLC and the prognosis of patients with MET‐amplified GC; (2) In our study, we performed Cox regression analysis on 58 patients with MET‐amplified GC who themselves had a poor prognosis, as opposed to unselected patients. The gene discussed is HSPG2; the disease is gastric cancer.