Delay in achieving milestone, aggressive behavior, speech delay, gibbus formation, short stature, respiratory/ear infection, coarse facial features, excessive hair growth, broad based gait/waddling, joint contractures, short stature, scoliosis/kyphosis, intellectual disability Small acquired porencephalic cyst left peri-sylvian mid parietal region, Hb = 11 g/dL (14–18), WBCs = 3900/cmm (4000–11000), Lymphocytes = 47% (20–45), Monocytes = 01% (2–6). Here, GSTM1 is linked to ear infection.