VIM and colorectal carcinoma: Overexpression of WT-Trx-1 induced EMT (decrease in E-cadherin and increase in vimentin), whereas overexpression of MT-Trx-1 had no effect on EMT marker expression in CRC cells (Figure 1F), and silencing of Trx-1 inhibited EMT (increased E-cadherin and decreased vimentin, Figure 1F).