Hence, the mechanism by which the FN1 3′-UTR upregulated THBS1 to achieve an oncogenic effect via the ceRNA network was specific to the FN1 protein, and the difference in the expression levels of THBS1 might be the core factor explaining the variations in the clinical significance of FN1 at the RNA and protein levels in GC. The gene discussed is THBS1; the disease is gastric cancer.