In summary, the FN1 3′-UTR in the ceRNA regulatory network might play a role in promoting metastasis mainly by sponging let-7i-5p and upregulating THBS1, as well as by affecting EMT and the expression levels of TGFβ1/2 and MMP2/9 in GC cells to a certain extent. Here, TGFB1 is linked to gastric cancer.