The clinical data presented here strongly suggested that cancer patients who did not achieve MPR had a greater percentage of Tim-3+cDC2 (p < 0.02 for NAC patients, and < 0.012 for NAPC patients), lower OS (p < 0.001 for NAC patients, and p = 0.002 for NAPC patients), and PFS. The gene discussed is HAVCR2; the disease is cancer.